ea0026p66 | Endocrine tumours and neoplasia | ECE2011
Fiebrich H-B
, de Jong J R
, Kema I P
, Koopmans K P
, Sluiter W J
, Dierckx R A J O
, Walenkamp A M E
, Brouwers A H
, de Vries E G E
, Links T P
Introduction: Positron emission tomography (PET) using 6-[F-18]fluoro-L-dihydroxyphenylalanine (18F-DOPA) has an excellent sensitivity to detect carcinoid tumor lesions. 18F-DOPA-tumor uptake and the levels of biochemical tumor markers are mediated by tumor endocrine metabolic activity. Therefore we evaluated whether total 18F-DOPA-tumor uptake on PET, defined as the whole-body metabolic burden (WBMTB) reflects tumor load per pat...